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Term Paper: Benchmark – Approved Drug by the FDA

Choose a drug that has been approved by the FDA within the past year.
Write a 1,000-1,250 word paper in which you:
Describe the drug approved by the FDA. Include the pharmacodynamics and pharmacokinetic properties of the chosen drug.
Provide an overview of the disease state for which the drug is used.
Describe what is different about this agent compared to currently available therapies.
Discuss the potential risks associated with this agent and any monitoring parameters that are necessary.
Decide whether you would personally prescribe this agent or stick with currently available alternatives.
You are required to cite five to 10 sources to complete this assignment. Sources must be published within the last 5 years and appropriate for the assignment criteria and nursing content.
Prepare this assignment according to the guidelines found in the APA Style Guide, located in the Student Success Center. An abstract is not required.

As indicated in the syllabus, there is an assignment this week. The assignment involves selecting and reviewing a drug that has been FDA-approved during the past year. You may go back to the beginning of 2018 if you wish, giving you more of a selection. Please review the syllabus for instructions on content, and the rubric for this assignment before you start writing your paper. Note that there is a requirement of citing 5 to 10 sources; these are evidence-based clinical sources (no lay public information-if any of your sources are written for the lay public, I will return your paper for rewriting and deduct one letter grade. I am serious about his assignment’s references). As with the previous assignment, use the APA style format for your paper. The assignment calls for a 1000-1250 word submission. Also keep in mind that this does not include the reference section, and the ‘Marsh parameters’ allows you some latitude regarding word count (but do not submit a ‘War & Peace’ size paper). Let’s say a maximum of 1400 words; I am more interested in content, and if it takes a bit more than 1250 words, then so be it.


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Benchmark-Approved Drug by the FDA

Ajovy is a drug that was approved on September 14, 2018, by the Food and Drug Administration (FDA) (Donelly & Hodge, 2019). The drug is administered as a prefilled syringe, allowing an individual to self-medicate, or turn to a health provider for the injection to be delivered. Ajovy is meant to be taken every month or every three months, dependent on the instructions that are given by the doctor or health care provider. Ajovy contains a monoclonal antibody called fremanezumab, which is meant to prevent some of the body’s proteins from functioning. It is also made from the body’s immune system cells (Roblee & VanerPluym, 2019). The pharmacodynamics of the Ajovy drug in clinical effects is unknown. The pharmacokinetics of Ajovy is that it reaches the maximum levels of plasma concentrations in about five to seven days after the drug is injected into the individual’s bloodstream. The steady concentrations achieved after constant dosages are seen after ….

Ajovy is used to help an individual in the prevention of both the chronic and episodic types of migraine headaches (Roblee & VanerPluym, 2019). Statistic results show that the use of the drug can help reduce the number of migraine days experienced by the individual to about a half. The clinical studies indicated that this was true for both the episodic and chronic types of …

Episodic migraines are defined as the headaches that may affect an individual about 14 days a month or less, while chronic migraines are described as the kind of migraines experience on more than 14 days a month (Roblee & VanerPluym, 2019). The general definition of a migraine is that it is a recurring type of headache that causes an individual pain that ranges from a moderate to a severe level due to the constant throbbing and pulsing. Migraines, whether chronic or episodic, are experienced as a throbbing pain on the side of the head. Sometimes the condition also causes weakness, nausea, and sensitivity to light and sound (Roblee & VanerPluym, 2019). There are various causes ….

There are various treatment methods available in the market as pertain to episodic and chronic migraines. The majorly used kind of treatment is abortive therapy. This form of treatment ranges from analgesics to triptans (Wachholtz, Malone & Pargament, 2017). Analgesics or painkillers are the types of drugs that may be used to achieve relief from pain, such as aspirin, which is a nonsteroidal anti-inflammatory drug (NSAID). Triptans, on the other hand, are a family of drugs that are administered orally intended to eliminate migraines and headaches. These abortive treatments tend to work better if they are administered at the starting point of the problem, however, since this type of treatment is …  

There are several recommended steps in the acute therapy treatment that can help individuals deal more effectively with severe migraines. The first step involves health providers educating the people prone to migraines on the need to actively participate in the management of their condition (Wachholtz et al., 2017). Secondly, they are encouraged to use migraine-specific agents such as triptans, which …

The approach to migraines is dependent on the severity of the attacks and the patient-specific factors, as well. For mild to moderate attacks, analgesics are recommended due to their practical nature and decreased the possibility of causing adverse side effects to the individual. This form of treatment is also less expensive as compared to triptans (Wachholtz et al., 2017). The second level is moderate to severe attacks. For this level of migraines, the triptans are thought to be the best option in cases where the patient is not suffering from nausea and vomiting (Voelker, 2018). However, if the patient’s migraines are accompanied by vomiting and severe nausea, an oral antiemetic drug shoul….

The third level of migraines is that variable attacks. They are referred to as variable attacks because the migraines vary in their association with nausea and vomiting, the time of onset, and severity. For this level, the victims may require more options for treating and managing the condition, since the attack may be chronic or episodic dependent on several factors (Wachholtz et al., 2017). The treatment administered should, therefore, include oral and nonoral medications. The last level is the emergency settings. These are characterized by migraines of unusual severity, in which the acute treatments have failed to provide the individual relief. For individuals who suffer from emergency level migraines, abortive therapy is highly recommended. In this case, the individuals are encouraged to seek medication that can help prevent the migraines rather than provide temporary relief to their discomfort. When Ajovy is compared to the other medication on the market, it is clear that it is among the best remedies out there since it can help an individual prevent the migraine attacks. This mode of treatment is much more efficient and effective in bettering the individual’s life, which is a significant factor in medication (Silberstein et al., 2019). It is also administered in regulated dosages reducing the possibility that the patient’s body may become resistant to…

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